National Collaborating Centre for Mental Health (UK). Treatment of patients with substance use disorders, second edition. Circumstances and toxicology of sudden or unnatural deaths involving alprazolam. Benzodiazepines: a major component in unintentional prescription drug overdoses with opioid analgesics. Alprazolam is relatively more toxic than other benzodiazepines in overdose. Isbister GK, O'Regan L, Sibbritt D, Whyte IM. Characteristics of alprazolam-related deaths compiled by a centralized state medical examiner. Shah NA, Abate MA, Smith MJ, Kaplan JA, Kraner JC, Clay DJ. Combining opioids and benzodiazepines: effects on mortality and severe adverse respiratory events. June 2018 Accessed: April 28, 2022.īoon M, van Dorp E, Broens S, Overdyk F. European Monitoring Centre of Drugs and Drug Addiction.
59 (12):1282-1501.Įuropean Monitoring Centre of Drugs and Drug Addiction. 2020 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 38th Annual Report. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Bronstein AC, Rivers LJ, et al. Physician Office Visits at Which Benzodiazepines Were Prescribed: Findings From 2014-2016 National Ambulatory Medical Care Survey. Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996-2013. īachhuber MA, Hennessy S, Cunningham CO, Starrels JL. Preliminary Data from the Drug Abuse Warning Network – April 2019-October 2020. Substance Abuse and Mental Health Services Administration. 70:1136–1141.ĭrug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. MMWR and Morbidity and Mortality Weekly Report. Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines - 38 States and the District of Columbia, 2019–2020. Liu S, O’Donnell J, Gladden RM, McGlone L, Chowdhury F. Fatal seizures after flumazenil administration in a patient with mixed overdose. Antidotes for toxicological emergencies: a practical review. Position paper: Single-dose activated charcoal. OctoAccessed: April 28, 2022.Ĭhyka PA, Seger D, Krenzelok EP, Vale JA.
12 (1):4-10.įDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class.
A Review of Alprazolam Use, Misuse, and Withdrawal. Propylene glycol toxicity: a severe iatrogenic illness in ICU patients receiving IV benzodiazepines: a case series and prospective, observational pilot study. Wilson KC, Reardon C, Theodore AC, Farber HW. Respiratory depression by midazolam and diazepam. 14:77-79.įorster A, Gardaz JP, Suter PM, Gemperle M. A Retrospective Review of Morbidity and Mortality Associated with Acute Benzodiazepine Withdrawal at a Midwestern Academic Medical Center. Thornton SL, Whitacre J, Pallo N, Roberts N, Oller L.
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